SKU # | E-AB-10380 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Applications | WB |
Product Details
Isotype | IgG |
Host | Rabbit |
Reactivity | Human,Mouse,Rat |
Applications | WB |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human HSPH1 |
Abbre | HSPH1 |
Synonyms | Antigen NY CO 25,Antigen NY-CO-25,DKFZp686M05240,He,Heat shock 105kD,Heat shock 105kD alpha,Heat shock 105kD beta,Heat shock 105kDa protein,Heat shock 105kDa protein 1,Heat shock 105kDa/110kDa protein 1,Heat shock 110 kDa protein,Heat shock 110kDa protein |
Swissprot | Q92598 |
Calculated MW | 97 kDa |
Cellular Localization | Cytoplasm. |
Concentration | 0.2 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer,Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
Applications | Recommended Dilution |
WB | 1:500-1:2000 |
Background
Heat shock protein 105 kDa is a protein that in humans is encoded by the HSPH1 gene.Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly.Inhibits HSPA8/HSC70 ATPase and chaperone activities.Highly expressed in testis.Present at lower levels in most brain regions, except cerebellum.Overexpressed in cancer cells.Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity.